Nowadays obesity has become a widespread, rising problem in the modern society.
Statistics of the Centers for Disease Control and Prevention shows that more than 36% of American adults and 17% of children and adolescents are obese. This means that their body mass index is higher than 30.
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Sedentary lifestyle, processed foods and unhealthy habits often make you to gain extra pounds, together with numerous health troubles.
Growing problem of obesity causes medical professionals and dietitians to develop numerous weight loss programs, eating plans and physical activities.
Strict diets and strategies that promise quick slimming can really help you fight off your weight-complexes in short period of time.
But the problem is that many of those, who have shed extra pounds following strong diets, have high risks of regaining these pounds in the consequence. This is called rebound effect.
Studies, conducted to explain this undesirable aftermaths, found that it's mainly about increase of ghrelin.
This hunger hormone is normally produced, when your stomach is empty. It sends signals to your brain, saying that it's time to have a meal.
When you change your dietary preferences drastically, the body activates adaptive mechanisms that leads to increased appetite and food cravings.
Scientists from the Mayo Clinic conducted a study in order to understand, whether it is possible to prevent rebound weight gain in those, who have already lost extra kilos.
Dr. Brimijoin together with his team tried to simulate this situation in mice.
The main idea was to study effects of enzyme butyrylcholinesterase in regulating excessive creation of hunger hormone ghrelin after successful weight loss.
Butyrylcholinesterase is a chemical, naturally released by the liver cells in order to remove toxic agents from the organism and metabolize certain drugs like cocaine.
Medical experts put DNA code of this chemical inside the neutralized virus and delivered it to the mice bodies, aiming to affect ghrelin levels.
Results showed that elevation of circulating butyrylcholinesterase leads to drop of appetite-increasing hormone. So, animals could adopt healthier eating habits and didn't gain weight.
These effects appeared after one enzyme-delivering procedure and were found to be long-acting.
This new finding may be a first step to developing more efficient weight-loss methods, as well as preventive treatments for diabetes, fatty liver disease and metabolic syndrome.
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Combination of calorie-restricting diets and hormonal regulation is a really good strategy for long-lasting weight control and prevention of global obesity crisis.
The BetterMe Team wants you and those close to you to live a healthy, happy life! Your health is a valuable thing; look after your body and your mind so that you can live your life to the fullest – Remember you only get one!
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